Monday 2 December 2013

HIV/AIDS


HIV is a name of virus short for Human Immunodeficiency Virus and AIDS is a name of disease caused by HIV stand for Acquired Immunodeficiency Syndrome. HIV is like other viruses same like flu and common cold and others. But there is an important difference over the time. Our immune system cleans most viruses but the human immune system can't seem to get rid of it. Scientists are still trying to figure out why. It is not inherited disease as the name shows.

Where HIV did came from?

        It has been identified a type of chimpanzee in West Africa as the source of HIV infection in humans.

How HIV spread?

    HIV is found in specific human body fluids. If any of those fluids enter the body, person can become infected with HIV. These fluids are given blow.
•    Blood
•    Semen (cum)
•    Pre-seminal fluid (pre-cum)
•    Breast milk
•    Vaginal fluids
•    Rectal (anal) mucous
It can be transmitted during sexual contact, child birth, breast feeding, pregnancy, infected injection, blood transfusion and organ transplant etc.

Symptoms of early stage:

•    Fever
•    Chills
•    Rash
•    Night sweats
•    Muscle aches
•    Sore throat
•    Fatigue
•    Swollen lymph nodes
•    Ulcers in the mouth

Progression to HIV:   

• Soaking night sweats
• Shaking chills or fever higher than 100 F (38 C) for several weeks
• Cough and shortness of breath
• Chronic diarrhea
• Persistent white spots or unusual lesions on your tongue or in your mouth
• Headaches
• Persistent, unexplained fatigue
• Blurred and distorted vision
• Weight loss
• Skin rashes or bump

Treatment:

There's no cure for HIV/AIDS, but a variety of drugs can be used in combination to control the virus such as

  1.  NNRTI, s (Non-nucleoside reverse transcriptase inhibitors) block a protein that needed by HIV to make copies of itself include efavirenz, etravirine, nevirapine.
  2. NRTI, s(Nucleoside reverse transcriptase inhibitors) Nucleoside reverse transcriptase inhibitors. NRTIs are faulty versions of building blocks that HIV needs to make copies of itself. For example Abacavir, tenofovir etc.
  3. PLS (Protease inhibitors) such as ritonavir.
  4. Entry or fusion inhibitors that block the entry into CD4 cells such as maraviroc.
  5. Integrase inhibitors that disable the protein that HIV uses to insert its genetic material into CD4 cell.

   



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